
Daphne Islands Vacations from $439
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
Better together
Save up to $1,045 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
The Latest Daphne Islands vacation packages
Price found within the past 48 hours. Click for updated prices.


Angermeyer Waterfront Inn
Price was $779, price is now $536 per person
$536
per person
Oct 31 - Nov 3
found 1 day ago
Roundtrip flight included
Guayaquil (GYE) to Isla Baltra (GPS)
9.4/10 Exceptional! (118 reviews)
Staff was very friendly and professional. They helped us with everything we asked for.
Reviewed on Jul 4, 2025

Mi Playa Galapagos Beachfront
Save 100% on your flight
Price was $1,176, price is now $816 per person
$816
per person
Oct 19 - Oct 22
just found
Roundtrip flight included
Guayaquil (GYE) to Isla Baltra (GPS)
8.8/10 Excellent! (5 reviews)
Beautiful view, close to restaurants bars and restaurants.
The owner was very nice, breakfast was wonderful.
Really luxury place. We miss that place..
Reviewed on May 11, 2023

La Casa de Marita
Price was $798, price is now $566 per person
$566
per person
Oct 31 - Nov 3
found 1 day ago
Roundtrip flight included
Guayaquil (GYE) to Isla Baltra (GPS)
9/10 Wonderful! (97 reviews)
We had a lovely night stay here. You’re on an island so some ants and bugs can be expected. This isn’t The Four Seasons so if you were looking for that you would be disappointed. What you will find staff willing to go above and beyond like Jonathan, who made our stay lovely. Love that you could just walk to the beach right behind the property. The peace and tranquillity you will find here is unmatched. I think this is the best place to stay on the island. We will definitely be returning.
Reviewed on May 14, 2025

Hotel Isamar Galapagos Beachfront
Price was $749, price is now $538 per person
$538
per person
Oct 31 - Nov 3
found 1 day ago
Roundtrip flight included
Guayaquil (GYE) to Isla Baltra (GPS)
9/10 Wonderful! (58 reviews)
We had a wonderful time! Breakfast was absolutely delicious, and we also enjoyed an amazing dinner during our stay. The cocktails were delicious and perfectly made. The staff provided excellent recommendations for things to do on Isabela Island, which really enhanced our experience. We truly appreciated the warm hospitality. The location right by the ocean was perfect, and everything was clean and well maintained.
Highly recommended!
Jenny , Pam and Rafael
Reviewed on Jul 22, 2025
Don't see what you're looking for?
See all available trips from Columbus to Daphne Islands
View all tripsDaphne Islands Hotel Deals

Royal Palm Galapagos, Curio Collection Hotel by Hilton
Km. 18 Via Puerto Ayora-Baltra Isla, Isla Santa Cruz, Santa Rosa, Galapagos
$293 nightly
The price is $322 total per night from Sep 1 to Sep 2
$322 total
Sep 1 - Sep 2
9.2/10 Wonderful! (49 reviews)
"The Royal Palm offers a truly immersive Galápagos experience—set inland on a stunning 100 acre property, far from the touristy feel of the ports. Recently under new ownership, the property is being refreshed: rooms are spacious and renovated, the pool has been redone, and quiet renovations are underway, ..."
Reviewed on Apr 20, 2025

Twin Hotel Galapagos
Bellavista Barrio los Túneles, Vía playa el Garrapatero, Bella Vista, Galapagos
Fully refundableReserve now, pay when you stay
8.4/10 Very Good! (41 reviews)
"This hotle is fantastic lovely people that work here Very helpful with booking tours ect . To rooms are so fantastic, comfortable bed can’t get any better and good breakfast."
Reviewed on Jul 19, 2025

Semilla Verde Boutique Hotel
Km 12 via Baltra, Bella Vista, Santa Cruz
$176 nightly
The price is $193 total per night from Aug 20 to Aug 21
$193 total
Aug 20 - Aug 21
9.8/10 Exceptional! (58 reviews)
Great stay
"An excellent stay. Cattya, the manager of the hotel was superb. She gave us timely information and organised the transfer of my luggage to Baltra airport whilst I was stuck at Isabela (due to tsunami alert). The food was lovely, both at breakfast and dinner. I would highly recommend to stay here. ..."
Reviewed on Jul 30, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
More vacations you might like
Explore a world of travel with Expedia
Explore a world of travel with Expedia
- Flights to North Seymour Island
- Flights to Baltra
- Flights from Quito (UIO) to Isla Baltra (GPS)
- Flights from Guayaquil (GYE) to Isla Baltra (GPS)
- Flights from New York (JFK) to Isla Baltra (GPS)
- Flights from Los Angeles (LAX) to Isla Baltra (GPS)
- Flights from Chicago (ORD) to Isla Baltra (GPS)
- Flights from San José (SJO) to Isla Baltra (GPS)
- Flights from Boston (BOS) to Isla Baltra (GPS)
- Flights from San Francisco (SFO) to Isla Baltra (GPS)
- Flights from Denver (DEN) to Isla Baltra (GPS)
- Flights from Miami (MIA) to Isla Baltra (GPS)
- Flights from Seattle (SEA) to Isla Baltra (GPS)
- Flights from San Juan (SJU) to Isla Baltra (GPS)
- Flights from Houston (IAH) to Isla Baltra (GPS)
- Flights from Seymour
- Flights from Dallas (DFW) to Isla Baltra (GPS)
- Flights from Washington (IAD) to Isla Baltra (GPS)
- Flights from Orlando (MCO) to Isla Baltra (GPS)
- Flights from Salt Lake City (SLC) to Isla Baltra (GPS)
- Flights from Raleigh (RDU) to Isla Baltra (GPS)
- Flights from Detroit (DTW) to Isla Baltra (GPS)
- Flights from Portland (PDX) to Isla Baltra (GPS)
- Flights from Minneapolis (MSP) to Isla Baltra (GPS)
- Flights from Phoenix (PHX) to Isla Baltra (GPS)
- Flights from Atlanta (ATL) to Isla Baltra (GPS)
- Flights from Philadelphia (PHL) to Isla Baltra (GPS)
- Flights from Kansas City (MCI) to Isla Baltra (GPS)
- Flights from Tampa (TPA) to Isla Baltra (GPS)
- Flights from New York (LGA) to Isla Baltra (GPS)
- Flights from Austin (AUS) to Isla Baltra (GPS)
- Flights from Lima (LIM) to Isla Baltra (GPS)
- Flights from San Diego (SAN) to Isla Baltra (GPS)
- Flights from Cuenca (CUE) to Isla Baltra (GPS)
- Flights from Santiago (SCL) to Isla Baltra (GPS)
- Flights from Panama City (PTY) to Isla Baltra (GPS)
- Flights from Cartagena (CTG) to Isla Baltra (GPS)
- Flights from Cincinnati (CVG) to Isla Baltra (GPS)
- Flights from Fort Lauderdale (FLL) to Isla Baltra (GPS)
- Flights from Baltimore (BWI) to Isla Baltra (GPS)
- Flights from Manta (MEC) to Isla Baltra (GPS)
- Flights from Medellín (MDE) to Isla Baltra (GPS)
- Flights from Sacramento (SMF) to Isla Baltra (GPS)
- Flights from San Antonio (SAT) to Isla Baltra (GPS)
- Flights from Toronto (YYZ) to Isla Baltra (GPS)
- Flights from San Cristobal (SCY) to Isla Baltra (GPS)
- Flights from Jacksonville (JAX) to Isla Baltra (GPS)
- Flights from Charlotte (CLT) to Isla Baltra (GPS)
- Flights from Grand Rapids (GRR) to Isla Baltra (GPS)
- Flights from Milwaukee (MKE) to Isla Baltra (GPS)
- Flights from Hartford (BDL) to Isla Baltra (GPS)
- Flights from New Orleans (MSY) to Isla Baltra (GPS)
- Flights from Indianapolis (IND) to Isla Baltra (GPS)
- Flights to Seymour
- Flights from Fayetteville (XNA) to Isla Baltra (GPS)
- Flights from Mexico City (MEX) to Isla Baltra (GPS)
- Flights from St. Louis (STL) to Isla Baltra (GPS)
- Flights from Rochester (ROC) to Isla Baltra (GPS)
- Flights from Washington (DCA) to Isla Baltra (GPS)
- Flights from Reno (RNO) to Isla Baltra (GPS)
- Flights from Norfolk (ORF) to Isla Baltra (GPS)
- Flights from Cancun (CUN) to Isla Baltra (GPS)
- Flights from Coca (OCC) to Isla Baltra (GPS)
- Flights from Louisville (SDF) to Isla Baltra (GPS)
- Flights from Buenos Aires (EZE) to Isla Baltra (GPS)
- Flights from Madison (MSN) to Isla Baltra (GPS)
- Flights from Las Vegas (LAS) to Isla Baltra (GPS)
- Flights from Liberia (LIR) to Isla Baltra (GPS)
- Flights from Belize City (BZE) to Isla Baltra (GPS)
- Flights from Huntsville (HSV) to Isla Baltra (GPS)
- Flights from Bogotá (BOG) to Isla Baltra (GPS)
- Flights from Guatemala City (GUA) to Isla Baltra (GPS)
- avianca Guayaquil (GYE) to Isla Baltra (GPS) flights
- Flights from West Palm Beach (PBI) to Isla Baltra (GPS)
- Flights from Orange County (SNA) to Isla Baltra (GPS)
- Flights from Vancouver (YVR) to Isla Baltra (GPS)
- Flights from Peoria (PIA) to Isla Baltra (GPS)
- Flights from Tucson (TUS) to Isla Baltra (GPS)
- Flights from Paris (CDG) to Isla Baltra (GPS)
- Flights from La Paz (LPB) to Isla Baltra (GPS)
- Flights from San Salvador (SAL) to Isla Baltra (GPS)
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.